KTRH (740 kHz AM) is a commercial radio station licensed to Houston, Texas and owned by iHeartMedia that airs a talk radio format. Programming is also heard on co-owned KODA's HD 2 channel at 99.1 MHz, and the station uses the iHeartRadio platform to stream its webcast. Its studios are located along the West Loop Freeway (I-610) in the city's Uptown district. The transmitter site is located at a four-tower facility in unincorporated Liberty County, off Cox Road in Dayton.

KTRH broadcasts with 50,000 watts around the clock, the highest power permitted by the Federal Communications Commission for commercial AM stations. But because it transmits on AM 740, a Canadian clear channel frequency, the station uses a directional antenna to protect Class A station CFZM in Toronto. During the day, the station provides at least secondary coverage to most of the southeast quadrant of Texas–as far west as Austin and San Antonio and as far north as College Station and Lufkin–as well as much of southwestern Louisiana. At night, the station switches to a directional pattern with a significant null to the east in order to protect CFZM, concentrating the signal in Houston, the Golden Triangle and Victoria.

KTRH is the Southern Texas primary entry point station for the Emergency Alert System.

KTRH is one of the oldest radio stations in the United States, and was first licensed to the city of Austin on April 22, 1922, as WCM.